Harry Potter dreamcast - Meryl Streep as everyone
If young Dumbledore turns up in those new films can we all agree to call him Youngledore?
*spider shaking dice in casino* come on, daddy longlegs needs a new pair of shoes and a new pair of shoes and a new pair of shoes and a new pair of shoes
Key Step in DNA Replication Deciphered
Building on earlier work exploring the complex choreography by which intricate cellular proteins interact with and copy DNA prior to cell division, scientists at the U.S. Department of Energy’s Brookhaven National Laboratory and collaborators have captured a key step-molecular images showing how the enzyme that unwinds the DNA double helix gets drawn to and wrapped around its target. Details of the research, published in the journal Nature Structural & Molecular Biology, enhance understanding of an essential biological process and may suggest ways for stopping cell division when it goes awry.
Protein machinery involved in DNA replication caught in action: The “origin recognition complex” (yellow), already activated by an initiation factor (brown), grabs onto the helicase core (purple blue) to load the helicase ring onto the DNA double helix (red). The background is a cryo-electron micrograph of many of these complexes (dark) frozen in ice. (Credit: Courtesy Brookhaven National Laboratory)
Jingchuan Sun, Cecile Evrin, Stefan A Samel, Alejandra Fernández-Cid, Alberto Riera, Hironori Kawakami, Bruce Stillman, Christian Speck, Huilin Li. Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA. Nature Structural & Molecular Biology, 2013; DOI: 10.1038/nsmb.2629
Warner Bros. announced on 12th September 2013 that J.K. Rowling would be making her screenwriting debut with ‘Fantastic Beasts and Where to Find Them’, the first in a new film series which is part of their expanded creative partnership with J.K. Rowling. The films will be…
I regret this post so much, that sometimes I wake up screaming, just thinking of it
are you okay
I’m still screaming
are u sad? feeling down? look at your hands. think about all the dogs they’ve petted. feel happy. so much happy.
Joking Bad: Jimmy Fallon’s Breaking Bad parody, featuring cameos by Bryan Cranston, Bob Odenkirk and Aaron Paul. Hilarious. Even has a pink teddy bear and a pizza toss.
check out my new joy division shirt shirt
i laughed a lot more than i should
A New Way To Tie a Scarf
Because fall is closing in on us quickly.
that’s a knot used in rock climbing that’s actually pretty badass it’s really secure